Tissue Factor Biological Functions : Coagulation Activity in Microparticles and Signaling with Focus On Migration and Apoptosis

Tissue Factor Biological Functions : Coagulation Activity in Microparticles and Signaling with Focus On Migration and Apoptosis

Background: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. TF is over-expressed on many malignant cells and apart from increasing the risk of thrombosis, the presence of TF/FVIIa also promotes the progression of cancer and metastasis by in...

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Bibliographic Details
Main Author: Åberg, Mikael
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinska vetenskaper 2008
Subjects:
Tissue factor
Apoptosis
Migration
Chemotaxis
Simvastatin
Platelet Derived Growth Factor
Cell Signaling
Microparticles
Prostasomes
Trombosis
Coagulation
Prostate Cancer
Breast Cancer
Caspase-3
Caspase-8
NFkappaB
PAR2
Transactivation
Monocytes
Clinical chemistry
Klinisk kemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9335
http://nbn-resolving.de/urn:isbn:978-91-554-7317-4

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9335
http://nbn-resolving.de/urn:isbn:978-91-554-7317-4

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