Antihypertrophic effect of hemin in deoxycorticosterone acetate-salt-induced hypertensive rat model

Antihypertrophic effect of hemin in deoxycorticosterone acetate-salt-induced hypertensive rat model

The application of the synthetic mineralocorticoid, deoxycorticosterone acetate (DOCA)-salt, to unilaterally nephrectomised rats induces severe hypertension due to volume-overload, and mimics human primary aldosteronism. Importantly, DOCA-salt hypertension is characterized by severe cardiac and rena...

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Bibliographic Details
Main Author: Jadhav, Ashok B.
Other Authors: Ndisang, Joseph Fomusi
Format: Others
Language:en
Published: University of Saskatchewan 2009
Subjects:
end-stage damage
pathology
DOCA-salt
hypertension
aldosterone
cardiac
renal
Online Access:http://library.usask.ca/theses/available/etd-01122009-115014/

Internet

http://library.usask.ca/theses/available/etd-01122009-115014/

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