Development and characterization of humanized and human forms of ELR-CXC chemokine antagonist, bovine CXCL8(3-74)K11R/G31P

Development and characterization of humanized and human forms of ELR-CXC chemokine antagonist, bovine CXCL8(3-74)K11R/G31P

Glu-Leu-Arg (ELR)-CXC chemokine-mediated neutrophil migration and activation plays a key role in many inflammatory diseases. Dysregulated neutrophil activation often leads to inflammatory responses such as acute lung injury (ALI) or acute respiratory distress syndrome (ARDS).<p> Previously, we...

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Bibliographic Details
Main Author: Zhao, Xixing
Other Authors: Singh, Baljit
Format: Others
Language:en
Published: University of Saskatchewan 2009
Subjects:
ELR-CXC chemokine
Antagonist
Lung
Inflammation
Neutrophil
Online Access:http://library.usask.ca/theses/available/etd-03122009-113704/

Internet

http://library.usask.ca/theses/available/etd-03122009-113704/

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