The <i>Aspergillus nidulans</i> Galf biosynthesis pathway is a promising drug target
Human systemic fungal infections are increasing, and causing high morbidity and mortality. Treatment is challenging because fungi share many metabolic pathways with mammals. Current antifungals are losing effectiveness due to drug resistance. In immunocompromised patients Aspergillus fumigatus cause...
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| Language: | en |
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University of Saskatchewan
2011
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| Online Access: | http://library.usask.ca/theses/available/etd-06082011-205124/ |