Histone deacetylase inhibitor regulation of gene expression

Histone deacetylase inhibitors (HDIs) are a group of chemo-preventive and chemo-therapeutic agents that have generated significant attention in clinical trials, given their ability to selectively induce cell cycle arrest, differentiation and/or apoptosis of tumor cells. Presently, these agents are p...

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Bibliographic Details
Main Author: Hirsch, Calley Lynn
Other Authors: Nazarali, Adil J.
Format: Others
Language:en
Published: University of Saskatchewan 2007
Subjects:
Online Access:http://library.usask.ca/theses/available/etd-06192007-164811/