The first step towards the development of an electrophoretic prion detector
In nanopore analysis, peptides and proteins can be detected by the change in current when single molecules interact with an α-hemolysin pore embedded in a lipid membrane. Studies into the effects of fluorenylmethoxycarbonyl (Fmoc), acetylation or proline modification to negatively charged α-helical...
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Format: | Others |
Language: | en |
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University of Saskatchewan
2011
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Online Access: | http://library.usask.ca/theses/available/etd-08082011-162258/ |