Regulation of heat shock factor 1 (HSF1) DNA-binding and transcription
Cellular stress invokes a protective response in which heat shock factor 1 (HSF1) is activated to increase heat shock protein (Hsp) expression. HSF1 exists as a latent monomer in unstressed cells. Upon stress HSF1 forms homotrimers, increasing its affinity for the heat shock DNA element upstream of...
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| Format: | Others |
| Language: | en |
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University of Saskatchewan
2003
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| Online Access: | http://library.usask.ca/theses/available/etd-09162003-231622/ |