Structure/anti-herpes activity studies of pyrimidine nucleoside analogs

Earlier studies have shown that 5-methoxymethyl-2$\sp\prime$deoxycytidine (MMdCyd (18)) and (E)-5-(2-bromovinyl)-2$\sp\prime$-deoxycytidine (BrVdCyd (17)) are potent and selective inhibitors of Herpes simples virus type-1 (HSV-1) replication with a high therapeutic index.<sup>1</sup> The...

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Bibliographic Details
Main Author: Zoghaib, Wajdi Michel
Other Authors: Tourigny, Guy
Format: Others
Language:en
Published: University of Saskatchewan 1996
Online Access:http://library.usask.ca/theses/available/etd-10212004-000825