Structure/anti-herpes activity studies of pyrimidine nucleoside analogs
Earlier studies have shown that 5-methoxymethyl-2$\sp\prime$deoxycytidine (MMdCyd (18)) and (E)-5-(2-bromovinyl)-2$\sp\prime$-deoxycytidine (BrVdCyd (17)) are potent and selective inhibitors of Herpes simples virus type-1 (HSV-1) replication with a high therapeutic index.<sup>1</sup> The...
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Format: | Others |
Language: | en |
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University of Saskatchewan
1996
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Online Access: | http://library.usask.ca/theses/available/etd-10212004-000825 |