Immunology of BCG vaccination in mice : implications for tuberculosis vaccination and for the use of BCG as a recombinant vaccine vector
The effect of vaccination dose on the immune response of mice to Mycobacterium bovis Bacille Calmette-Guerin (BCG) was examined. To assess T helper cell-type 1 (Th1) and -type 2 (Th2) responses, a very sensitive ELISPOT assay was developed. Using this assay, the numbers of BCG-specific interferon γ-...
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| Format: | Others |
| Language: | en |
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University of Saskatchewan
2000
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| Online Access: | http://library.usask.ca/theses/available/etd-10212004-001934 |