The role for the p85 subunit of PI3kinase in the regulation of rab proteins

The role for the p85 subunit of PI3kinase in the regulation of rab proteins

Upon activation by the platelet-derived growth factor receptor (PDGFR), phosphatidylinositol 3'-kinase (PI3K) converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 3,4,5-trisphosphate to activate the PI3K/Akt cellular survival signalling pathway within cells. The p85 subunit of...

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Bibliographic Details
Main Author: King, Jennifer C
Other Authors: Mousseau, Darrell D.
Format: Others
Language:en
Published: University of Saskatchewan 2009
Subjects:
PDGFR Trafficking
Endocytosis
Rab5
Rab4
PI3K
GAP activity
GTPases
Online Access:http://library.usask.ca/theses/available/etd-11172008-093707/

Internet

http://library.usask.ca/theses/available/etd-11172008-093707/

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