Engineering intracellular antibody libraries

The goal of this research is to understand how three different parameters affect single chain variable fragment (scFv) binding capacity. The parameters that were varied include the number of variable complementarity determining regions (CDRs), the number amino acids used to diversify CDRs, and confi...

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Bibliographic Details
Main Author: Bernhard, Wendy Lynn
Other Authors: Peng, Ding-Yu
Format: Others
Language:en
Published: University of Saskatchewan 2008
Subjects:
Online Access:http://library.usask.ca/theses/available/etd-11172008-111943/