Application of PI-deconvolution to the screening of protein ligand combinatorial libraries using the yeast-two-hybrid assay
Reagents that bind proteins are applicable in biology for detection of molecules, perturbation of signaling pathways and development of small-molecule pharmaceuticals. Protein ligands interact with proteins, inhibiting or altering their function. They are isolated from combinatorial libraries to int...
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| Format: | Others |
| Language: | en |
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University of Saskatchewan
2008
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| Online Access: | http://library.usask.ca/theses/available/etd-11242008-141444/ |