Role of methylglyoxal in the pathogenesis of hypertension
Methylglyoxal (MG), a metabolite of glucose, causes non-enzymatic glycation of proteins to form irreversible advanced glycation end products (AGEs). Increased MG production, which in turn gives rise to AGEs, has been linked to the development of complications in diabetes. However, the role of MG and...
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| Format: | Others |
| Language: | en |
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University of Saskatchewan
2007
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| Online Access: | http://library.usask.ca/theses/available/etd-12132007-230430/ |