The effects of plasmid DNA and immunostimulatory CpG motifs on immune surveillance in sheep lymph nodes

This Ph.D. dissertation examined the effects of bacterial DNA on immune surveillance in ovine lymph nodes (LN). The first study identified long-term changes in lymph nodes following exposure to plasmid DNA. Treated lymph nodes were heavier and had larger medullary areas. Furthermore, medullary cord...

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Bibliographic Details
Main Author: Uwiera, Richard Robert Ernest
Other Authors: Middleton, Dorothy M.
Format: Others
Language:en
Published: University of Saskatchewan 2009
Online Access:http://library.usask.ca/theses/available/etd-12182008-125045/