Rb-Raf-1 Interaction as a Therapeutic Target for Proliferative Disorders
The retinoblastoma tumor suppressor protein, Rb, is a key regulator of the mammalian cell cycle and its inactivation facilitates S-phase entry. Rb is inactivated through multiple waves of phosphorylation, mediated mainly by kinases associated with D and E type cyclins in the G1 phase of the cell cyc...
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Scholar Commons
2008
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| Online Access: | https://scholarcommons.usf.edu/etd/335 https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=1334&context=etd |