BRCA1 185delAG Mutant Protein, BRAt, Amplifies Caspase-Mediated Apoptosis and Maspin Expression in Ovarian Cells

Ovarian cancer is a deadly disease that kills an estimated 15,000 women annually in the United States. It is estimated that approximately 10% of ovarian cancers are due to familial inheritance. The most commonly mutated genes in familial ovarian cancer are BRCA1 and BRCA2. It has been reported that...

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Bibliographic Details
Main Author: O'Donnell, Joshua D
Format: Others
Published: Scholar Commons 2008
Subjects:
Akt
Online Access:https://scholarcommons.usf.edu/etd/433
https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=1432&context=etd