BRCA1 185delAG Mutant Protein, BRAt, Amplifies Caspase-Mediated Apoptosis and Maspin Expression in Ovarian Cells
Ovarian cancer is a deadly disease that kills an estimated 15,000 women annually in the United States. It is estimated that approximately 10% of ovarian cancers are due to familial inheritance. The most commonly mutated genes in familial ovarian cancer are BRCA1 and BRCA2. It has been reported that...
Main Author: | |
---|---|
Format: | Others |
Published: |
Scholar Commons
2008
|
Subjects: | |
Online Access: | https://scholarcommons.usf.edu/etd/433 https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=1432&context=etd |