Human Topoisomerase II Alpha Nuclear Export Is Mediated by Two Crm-1 Dependent Nuclear Export Signals
Resistance to chemotherapeutic drugs is a major obstacle in the treatment of leukemia and multiple myeloma. We have previously found that myeloma and leukemic cells in transition from low-density log phase conditions to high-density plateau phase conditions exhibit a substantial export of endogenous...
Main Author: | |
---|---|
Format: | Others |
Published: |
Scholar Commons
2004
|
Subjects: | |
Online Access: | https://scholarcommons.usf.edu/etd/1276 https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=2275&context=etd |