Human Topoisomerase II Alpha Nuclear Export Is Mediated by Two Crm-1 Dependent Nuclear Export Signals

Resistance to chemotherapeutic drugs is a major obstacle in the treatment of leukemia and multiple myeloma. We have previously found that myeloma and leukemic cells in transition from low-density log phase conditions to high-density plateau phase conditions exhibit a substantial export of endogenous...

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Bibliographic Details
Main Author: Turner, Joel G
Format: Others
Published: Scholar Commons 2004
Subjects:
Online Access:https://scholarcommons.usf.edu/etd/1276
https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=2275&context=etd