Analysis of E2F1 target genes involved in cell cycle and apoptosis
One of the main results of Rb-E2F pathway disruption is deregulation of the E2F family of transcription factors, which can lead to inappropriate proliferation, oncogenic transformation, or the induction of apoptosis. Given the potential negative biological effects associated with deregulated E2F act...
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| Format: | Others |
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Scholar Commons
2007
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| Online Access: | http://scholarcommons.usf.edu/etd/2178 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3177&context=etd |