Chromosome missegregation in Alzheimer's disease caused by presenilin 1

Mutations in the presenilin 1 gene account for most early-onset familial Alzheimer's disease (FAD). The presenilins and AD may also be related through a common involvement in the cell cycle. Here we report that one important aspect of the cell cycle---proper chromosome segregation---is dependen...

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Bibliographic Details
Main Author: Boeras, Debrah I
Format: Others
Published: Scholar Commons 2005
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/2786
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3785&context=etd