Chromosome missegregation in Alzheimer's disease caused by presenilin 1
Mutations in the presenilin 1 gene account for most early-onset familial Alzheimer's disease (FAD). The presenilins and AD may also be related through a common involvement in the cell cycle. Here we report that one important aspect of the cell cycle---proper chromosome segregation---is dependen...
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Format: | Others |
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Scholar Commons
2005
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Online Access: | http://scholarcommons.usf.edu/etd/2786 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3785&context=etd |