Attenuation of bromobenzene-induced hepatotoxicity by poly(adp-ribose) polymerase inhibitors
Previous studies have shown extensive cellular damage can activate poly(ADP-ribose) polymerase-1 (PARP-1) and cause a rapid decrease in the levels of NAD+ and ATP, thereby preventing apoptosis and promoting necrosis and inflammation. The purpose of this study was to extend previous observations that...
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| Format: | Others |
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Scholar Commons
2005
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| Online Access: | http://scholarcommons.usf.edu/etd/2911 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3910&context=etd |