Lead Discovery and Optimization Strategies Towards the Development of 4(1H)-Quinolones and 1,2,3,4-Tetrahydroacridone Analogs with Antimalarial Activity

Lead Discovery and Optimization Strategies Towards the Development of 4(1H)-Quinolones and 1,2,3,4-Tetrahydroacridone Analogs with Antimalarial Activity

The goal of our research endeavor was to successfully employ modern lead discovery and optimization strategies towards the development and identification of compounds possessing antimalarial activity. Preliminary data from in vitro screening at the Walter Reed Army Institute of Research identified s...

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Bibliographic Details
Main Author: Cross, Richard Matthew
Format: Others
Published: Scholar Commons 2011
Subjects:
1,2,3,4-Tetrahydroacridone
4(1H)-Quinolone
Antimalarial
Lead Identification
Lead Optimization
SAR
American Studies
Art Practice
Arts and Humanities
Biochemistry
Organic Chemistry
Online Access:http://scholarcommons.usf.edu/etd/3051
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=4246&context=etd

Internet

http://scholarcommons.usf.edu/etd/3051
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=4246&context=etd

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