Targeting α4 Integrin Containing Complexes in Multiple Myeloma Using Peptidomimetics
In our previous work we demonstrated that the integrin antagonist, HYD1, induced necrotic cell death in myeloma cell lines in vitro and in vivo as a single agent. In order to further delineate biomarkers of response to HYD1 we developed an isogenic drug resistant variant named H929-60. We show tha...
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| Format: | Others |
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Scholar Commons
2012
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| Online Access: | http://scholarcommons.usf.edu/etd/4314 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=5510&context=etd |