Functional and mutational analysis of human RecQ-Like DNA helicases in Saccharomyces cerevisiae

RecQ-like proteins are a family of DNA helicases that are evolutionary conserved from prokaryotes to eukaryotes. A large amount of experimental evidence suggests these proteins have a major role in the maintenance of genome stability. In humans five RecQ like helicase have been identified (RecQL1, B...

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Bibliographic Details
Main Author: Mirzaei-Souderjani, Hamed
Format: Others
Published: Scholar Commons 2013
Subjects:
BLM
Online Access:http://scholarcommons.usf.edu/etd/4547
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=5744&context=etd