Elucidation of the Role of Poly(ADP-Ribose) Polymerase in Drug-Induced Toxicity

Drug toxicity may cause liver injury, resulting in damage to cells and tissues. This damage can lead to cytotoxic events that may result in an activation of poly (ADP-ribose) polymerase (PARP). A study was conducted to determine if cocaine and acetaminophen toxicity lead to DNA damage and to the act...

Full description

Bibliographic Details
Main Author: Haire, Kambria
Format: Others
Published: Scholar Commons 2015
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/5959
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=7155&context=etd