Elastin-Like Polypeptide Fusion Tag as a Protein-Dependent Solubility Enhancer of Cysteine-Knot Growth Factors
Elastin-like peptide (ELP) fusions promote therapeutic delivery and efficacy. Recombinant proteins, like neurotrophins, lack bioavailability, have short in vivo half-lives, and require high manufacturing costs. Fusing recombinant proteins with genetically encodable ELPs will increase bioavailability...
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| Format: | Others |
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Scholar Commons
2018
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| Online Access: | https://scholarcommons.usf.edu/etd/7629 https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=8826&context=etd |