Structure-Activity Relationships of Retinoids in Developmental Toxicology
The teratogenic potency of retinoid analogs was determined in Syrian hamsters and compared to the teratogenic potency of all-trans-retinoic acid (all-trans.-RA, ED50 = 10.5 mg/kg). A total of 15 analogs having variations in the cyclohexene ring were evaluated following various amounts of single oral...
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Format: | Others |
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DigitalCommons@USU
1988
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Online Access: | https://digitalcommons.usu.edu/etd/4042 https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=5060&context=etd |