Structure-Activity Relationships of Retinoids in Developmental Toxicology

The teratogenic potency of retinoid analogs was determined in Syrian hamsters and compared to the teratogenic potency of all-trans-retinoic acid (all-trans.-RA, ED50 = 10.5 mg/kg). A total of 15 analogs having variations in the cyclohexene ring were evaluated following various amounts of single oral...

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Bibliographic Details
Main Author: Howard, W. Brian
Format: Others
Published: DigitalCommons@USU 1988
Subjects:
Online Access:https://digitalcommons.usu.edu/etd/4042
https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=5060&context=etd