Endogenous gypsy insulators mediate higher order chromatin organization and repress gene expression in Drosophila
Chromatin insulators play a role in gene transcription regulation by defining chromatinboundaries. Genome-wide studies in Drosophila have shown that a large proportion of insulator sites are found in intergenic DNA sequences, supporting a role for these elements as boundaries. However, approximately...
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Format: | Others |
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Trace: Tennessee Research and Creative Exchange
2011
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Online Access: | http://trace.tennessee.edu/utk_graddiss/1150 |