Endogenous gypsy insulators mediate higher order chromatin organization and repress gene expression in Drosophila

Chromatin insulators play a role in gene transcription regulation by defining chromatinboundaries. Genome-wide studies in Drosophila have shown that a large proportion of insulator sites are found in intergenic DNA sequences, supporting a role for these elements as boundaries. However, approximately...

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Bibliographic Details
Main Author: Zhang, Shaofei
Format: Others
Published: Trace: Tennessee Research and Creative Exchange 2011
Subjects:
Online Access:http://trace.tennessee.edu/utk_graddiss/1150