High-sensitivity spectral fluorescence lifetime imaging for resolving spectroscopically overlapping species

The capability to resolve the contributions from spectroscopically overlapping fluorophores has enabled significant breakthroughs in cellular imaging. However, commercial microscopes for this purpose use analog light detection with least squares curve-fitting analysis and improvements in sensitivity...

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Bibliographic Details
Main Author: Crawford, Justin L.
Format: Others
Published: Trace: Tennessee Research and Creative Exchange 2009
Subjects:
Online Access:http://trace.tennessee.edu/utk_gradthes/36