Synthesis of 123-Iodine Labeled Rofecoxib Analogues: Potential Nuclear Medicine Imaging Agents

Single photon emission computed tomography (SPECT) is a medical imaging technique which provides three-dimensional images ofliving systems after introduction ofa radiolabeled pharmaceutical. Rofecoxib (4-[ 4-methylsulphonylphenyl]-3phenylfuran-2(SH)-one) is an inhibitor of the cycloxygenase-2 enzyme...

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Bibliographic Details
Main Author: Belue, Brandy U
Format: Others
Published: Trace: Tennessee Research and Creative Exchange 2005
Subjects:
Online Access:http://trace.tennessee.edu/utk_gradthes/584