Defining the function of the Chediak-Higashi syndrome related protein, LvsB, in Dictyostelium discoideum : functional interactions that antagonize vesicle fusion
Lesions in the human Lyst gene are associated with the lysosomal disorder Chediak Higashi Syndrome. The absence of Lyst causes the formation of enlarged lysosome related compartments in all cells. This defect results in severe immunodeficiency, neurological dysfunction, and ultimately in death. D...
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Format: | Others |
Language: | en_US |
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2013
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Online Access: | http://hdl.handle.net/2152/21455 |