Mechanistic studies and drug discovery for eEF-2 kinase

eEF-2K, also known as CaM kinase-III, is an atypical protein kinase which negatively regulates the global rate of protein synthesis through the phosphorylation and inactivation of its substrate eEF-2. Recently eEF-2K has been validated as a novel target for anti-cancer therapy. However, a detailed...

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Bibliographic Details
Main Author: Devkota, Ashwini Kumar
Format: Others
Language:en_US
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/2152/22246