Multi-cycle cisplatin treatment alters spermatogonial functional stem cell behavior and niche

A typical clinical cis-diamminedichloroplatinum (II) (cisplatin) dosing regimen consists of repeated cycles of five to seven daily low dose treatments followed by a one to two week recovery period. While effective, this dosing structure results in a prolonged, and sometimes permanent, infertility in...

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Bibliographic Details
Main Author: Harman, James Gregory
Format: Others
Language:en_US
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/2152/23101