Zinc interactions with allosteric modulators at the glycine receptor
The glycine receptor (GlyR) is a ligand-gated ion channel member of the Cys-loop receptor superfamily, responsible for inhibitory neurotransmission in the brain and spinal cord. Zinc is a potent allosteric modulator of GlyR function, enhancing GlyR activity at low nM to 10[mu]M concentrations while...
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| Format: | Others |
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2014
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| Online Access: | http://hdl.handle.net/2152/25830 |