DNA cleavage chemistry of pyridinium-based heterocyclic skipped aza-enediynes and targeting SV40 large T-antigen G-quadruplex DNA helicase activity by G-quadruplex interactive agents
Two diverse works regarding DNA-Drug Interaction are presented here. The first portion deals with covalent interactions between compounds that are derivatives of heterocyclic aza-enediynes and DNA (conventional Watson-Crick base paired double stranded DNA) and the second is related to non-covalent...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | English |
| Published: |
2008
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/2152/3711 |