Toward group II intron-based genome targeting in eukaryotic cells

Mobile group II introns consist of a self-splicing RNA molecule and an intron-encoded protein with reverse transcriptase activity that function together in an RNP and catalyze the insertion of the intron into specific DNA target sites by a process known as retrohoming. The mechanism of insertion req...

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Bibliographic Details
Main Author: Vernon, Jamie Lee
Format: Others
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/2152/7563