Molecular mechanisms of choroid fissure closure and ventral retina formation in the zebrafish eye

During optic cup morphogenesis, the neuroectodermal layers of the optic vesicle (OV) invaginate ventrally, and fuse at the choroid fissure (CF) along the proximo-distal axis such that the retina and retinal pigment epithelium (RPE) are confined within the cup. Failure of CF closure results in colobo...

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Bibliographic Details
Main Author: Lee, Jiwoon
Format: Others
Language:English
Published: 2011
Subjects:
Shh
Online Access:http://hdl.handle.net/2152/9921