Integrin alphα5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish

Fibronectin (fn) and integrin α5 (itgα5) are both key players in cell adhesion and intracellar signaling, however the specific in vivo role of these proteins has never been analyzed in the vertebrate lens. The results presented here indicate that Fn1 and Itgα5 proteins are essential for the proper...

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Bibliographic Details
Main Author: Hayes, Julie Marie
Format: Others
Language:English
Published: 2010
Subjects:
FAK
Online Access:http://hdl.handle.net/2152/ETD-UT-2010-08-1966