The determinants of chain type specificity and the mechanism of polyubiquitination by HECT E3s

Ubiquitination is a post-translational modification that can take several forms. Some proteins are modified with a single ubiquitin molecule, while others are modified with polyubiquitin chains. Each type of ubiquitination is thought to have distinct biological functions. The best-characterized type...

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Bibliographic Details
Main Author: Kim, Hyung Cheol
Format: Others
Language:English
Published: 2011
Subjects:
UBD
Online Access:http://hdl.handle.net/2152/ETD-UT-2010-12-2427