Novel high-throughput screening methods for the engineering of hydrolases

Enzyme engineering relies on changes in the amino acid sequence of an enzyme to give rise to improvements in catalytic activity, substrate specificity, thermostability, and enantioselectivity. However, beneficial amino acid substitutions in proteins are difficult to rationally predict. Large numbers...

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Bibliographic Details
Main Author: Gebhard, Mark Christopher
Format: Others
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/2152/ETD-UT-2011-05-2812