Insights into the Molecular Mechanisms of Phospholipase D-Mediated Cancer Cell Survival

The production of bioactive lipids by phospholipases has long been appreciated as an important mode of cellular communication. Phospholipase D (PLD) enzymes hydrolyze phosphatidylcholine to generate a choline headgroup and the important lipid second messenger, phosphatidic acid (PtdOH). PLD family m...

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Bibliographic Details
Main Author: Bruntz, Ronald Chase
Other Authors: Brian E. Wadzinski
Format: Others
Language:en
Published: VANDERBILT 2014
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-01142014-193543/