Mechanisms of glucagon secretion in mouse pancreatic alpha-cells
Under hypoglycemic conditions, glucagon is secreted from α-cells, within pancreatic islets of Langerhans, to stimulate hepatic glucose output and, therefore, to restore proper glycemia. Once normoglycemia is reestablished, glucagon release is inhibited. Two general models have been proposed to accou...
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Language: | en |
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VANDERBILT
2011
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-02212011-191009/ |