Genetic Predisposition to Prostate Cancer: The Contribution of the HPCX locus and TGFB1 gene

There is a significant genetic component to prostate cancer (PrCa) risk. Multiple epidemiologic and linkage studies suggest X-linked heritability. Located at chromosome Xq27-28, HPCX has been identified as a PrCa susceptibility locus in multiple independent studies. We hypothesized that HPCX harbors...

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Bibliographic Details
Main Author: Yaspan, Brian Louis
Other Authors: Jeffrey R. Smith
Format: Others
Language:en
Published: VANDERBILT 2008
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03052008-111718/