The Mechanobiology of Notch1 Deficiency in Calcific Aortic Valve Disease

Calcific aortic valve disease (CAVD) is the predominant valvular disease in the developed world, affecting over five million individuals in the United States alone and manifests itself as a progressive disease resulting in the obstruction of left ventricular outflow, decreased cardiac output, and ev...

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Bibliographic Details
Main Author: Chen, Joseph
Other Authors: W. David Merryman
Format: Others
Language:en
Published: VANDERBILT 2015
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03192015-155246/