Investigations of the enzymatic mechanisms and inhibition of prostaglandin E2 biosynthesis

Polyunsaturated fatty acids can be liberated from phospholipids in the membrane bilayer and enzymatically converted to oxygenated bioactive lipid compounds that contribute to the pathology, or in some cases, the resolution of inflammation. One of the most well-studied enzymatic pathways, the cycloox...

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Bibliographic Details
Main Author: Goodman, Michael Christopher
Other Authors: John A McLean
Format: Others
Language:en
Published: VANDERBILT 2018
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03202018-132825/