MOLECULAR MECHANISMS OF ADAR2 LOCALIZATION AND SUBSTRATE SPECIFICITY

ADAR2-mediated adenosine-to-inosine (A-to-I) RNA editing can affect the coding potential, splicing pattern, stability, and localization of the targeted RNA transcripts. ADAR2 contains two double-stranded RNA binding motifs (dsRBM) and a conserved adenosine deaminase domain. To investigate how the ds...

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Bibliographic Details
Main Author: Xu, Ming
Other Authors: Randy D. Blakely
Format: Others
Language:en
Published: VANDERBILT 2006
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03252006-110338/