Functional Dynamics of Replication Protein A in initiation of SV40 DNA Replication

Human replication protein A (RPA) is a single-stranded DNA (ssDNA) binding protein involved in DNA metabolism. RPA binds ssDNA transiently during initiation of DNA replication. When this dissertation research began, the mechanisms of RPA loading and displacement were not known. Two SV40 T antigen-bi...

Full description

Bibliographic Details
Main Author: Jiang, Xiaohua
Other Authors: James G. Patton
Format: Others
Language:en
Published: VANDERBILT 2008
Subjects:
Online Access:http://etd.library.vanderbilt.edu//available/etd-03252008-092729/