Functional Dynamics of Replication Protein A in initiation of SV40 DNA Replication
Human replication protein A (RPA) is a single-stranded DNA (ssDNA) binding protein involved in DNA metabolism. RPA binds ssDNA transiently during initiation of DNA replication. When this dissertation research began, the mechanisms of RPA loading and displacement were not known. Two SV40 T antigen-bi...
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Format: | Others |
Language: | en |
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VANDERBILT
2008
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Online Access: | http://etd.library.vanderbilt.edu//available/etd-03252008-092729/ |