ALCAM Dynamically Regulates Tumor Cell Adhesion Through Differential Proteolysis and a Novel Binding Partner, Tetraspanin CD151

Metastasis persists as a significant unsolved hurdle in cancer treatment, with greater than 90% of cancer-related deaths attributed to metastasis. In order for cells to successfully metastasize, they must dynamically regulate cell adhesion. However, cell adhesion molecules are rarely mutated or dele...

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Bibliographic Details
Main Author: Hebron, Katie Elizabeth
Other Authors: Simon Hayward
Format: Others
Language:en
Published: VANDERBILT 2018
Subjects:
Online Access:http://etd.library.vanderbilt.edu/available/etd-03262018-125428/