Role of PAK2 promoting intrinsic tumor cell motility and worsening patient outcomes in non-small cell lung cancer
Cell motility is a process tightly linked to tumor metastasis. The p21-activated kinases (PAKs) are modulators of cell motility commonly overexpressed and hyperactive in various malignancies. We investigated whether increased PAK2 expression and phosphorylation levels enhance cancer cell motility,...
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| Format: | Others |
| Language: | en |
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VANDERBILT
2018
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| Online Access: | http://etd.library.vanderbilt.edu/available/etd-03262018-144420/ |