Role of PAK2 promoting intrinsic tumor cell motility and worsening patient outcomes in non-small cell lung cancer

Role of PAK2 promoting intrinsic tumor cell motility and worsening patient outcomes in non-small cell lung cancer

Cell motility is a process tightly linked to tumor metastasis. The p21-activated kinases (PAKs) are modulators of cell motility commonly overexpressed and hyperactive in various malignancies. We investigated whether increased PAK2 expression and phosphorylation levels enhance cancer cell motility,...

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Bibliographic Details
Main Author:	Bissonnette, Adam Marc
Other Authors:	Vito Quaranta
Format:	Others
Language:	en
Published:	VANDERBILT 2018
Subjects:	Cancer Biology
Online Access:	http://etd.library.vanderbilt.edu/available/etd-03262018-144420/

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