WASP FAMILY MEMBERS AND THE ARP2/3 COMPLEX ARE CRITICAL REGULATORS OF ACTIN IN THE DEVELOPMENT OF DENDRITIC SPINES AND SYNAPSES IN HIPPOCAMPAL NEURONS
Changes in the number, size, and shape of dendritic spines are associated with synaptic plasticity, which underlies cognitive functions such as learning and memory. This plasticity is attributed to reorganization of actin, but the molecular signals that regulate this process are poorly understood. I...
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Language: | en |
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VANDERBILT
2008
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Online Access: | http://etd.library.vanderbilt.edu/available/etd-03272008-132508/ |